CTZ paste for endodontic approach to deciduous teeth: A literature review
DOI:
https://doi.org/10.47990/alop.v12i1.218Keywords:
tooth, deciduous, endodontics, anti-bacterial agents, materials testing, clinical trialAbstract
Introduction: The irreversible pulp changes in primary teeth represent a challenge to endodontics in pediatric dentistry. Based on the Lesion Sterilization and Tissue Repair approach (LSTR), a non-instrumental endodontic treatment (NIET) of primary teeth root canals using an antibiotic paste has been proposed. The CTZ antibiotic paste, which contains a mixture of chloramphenicol, tetracycline, zinc oxide and eugenol, has potential for use in pediatric patients. Objective: The objective of this work is to present a literature review on the CTZ antibiotic paste, covering antimicrobial capacity, biocompatibility, and clinical aspects. Methods: An electronic search on PUBMED, BVS, WEB OF SCIENCE, COCHRANE y SCOPUS databases using the terms “ctz paste”, “ctz”, “deciduous teeth” and “primary molars” without language restrictions and publication date between 2015 and January 2021. Results: After removing duplicates, a total of 13 articles were included. The CTZ paste showed satisfactory antimicrobial activity on Enterecoccus faecalis, Staphylococcus aureus, Klebisiella pneumonia, Escherichia coli and Candida albicans. In vivo and in vitro studies have demonstrated that the paste presents good biocompatibility. The frequency of clinical success varied from 37% to 100% and radiographic success from 29,7% to 97,4%. Conclusion: Although more studies are needed to contribute to the body of evidence, the CTZ antibiotic paste demonstrated antimicrobial activity, biocompatibility and satisfactory clinical results and may be an alternative for cases of pulp involved primary teeth, including in public health.
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